Dr. Gross is a patent agent in the Biotechnology/Chemical Group where he assists in the preparation and prosecution of U.S. and foreign patent applications. His areas of technical experience include organic chemistry, medicinal chemistry, drug discovery and ion channel pharmacology.
Prior to joining Sterne Kessler, Dr. Gross was employed by a biopharmaceutical company as a Senior Research Investigator. He focused on small molecule drug discovery in cardiovascular and pain therapeutic areas and brings ten years of industrial research and development experience to his practice. Also, Dr. Gross contributed to several programs that advanced new chemical entities into human clinical trials.
Dr. Gross conducted postdoctoral research studies at Duke University and Los Alamos National Laboratories. At Duke, he studied asymmetric catalytic hydrogenation reactions to devise a practical synthesis of β-branched ��-amino acids. At Los Alamos, he demonstrated asymmetric reductions could be carried out in supercritical fluids. Dr. Gross pursued graduate studies at the University of Virginia where he investigated the synthetic utility of heterobimetallic Fischer carbene complexes.
Additionally, Dr. Gross is a named inventor on twenty-five United States patents.
"A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat" Gross, M.F. et al., PNAS 2007.
"Aryl Sulfonamido Indane Inhibitors of the Kv1.5 Ion Channel" Gross, M. F.; Beaudoin, S.; McNaughton-Smith, G.; Amato, G. S.; Castle, N. A.; Huang, C.; Zou, A.; Yu, W. Bioorganic & Medicinal Chemistry Letters 2007.
“Asymmetric Catalytic Routes to Chiral Building Blocks of Medicinal Interest” Burk, M. J.; Gross, M. F.; Harper, T. G. P.; Kalberg, C. S.; Lee, J. R.; Martinez, J. P. Pure Appl. Chem. 1996, 68, 37-44.
“Asymmetric Catalytic Synthesis of ��-Branched Amino Acids via Highly Enantioselective Hydrogenation Reactions” Burk, M. J.; Gross, M. F.; Martinez, J. P. J. Am. Chem. Soc. 1995, 117, 9375-9376.
“Asymmetric Catalytic Hydrogenation Reactions in Supercritical Carbon Dioxide” Burk, M. J.; Feng, S. G.; Gross, M. F.; Tumas, W. J. Am. Chem. Soc. 1995, 117, 8277-8278.
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